SPECIALIZED PET CT RADIOPHARMACEUTICALS

 This is the standard PET used in well differentiated neuroendocrine tumours (WHO grade 1 or 2). These tumor cells over expressed SSTR receptors 2,3,5. 68Ga-DOTANOC or DOTATATE both can be used to target these SSTR receptors. DOTANOC PET is used for staging, treatment response assessment, suspected recurrence and restaging. DOTANOC PET is also useful in medullary thyroid carcinoma (MTC) and pheochromocytoma,  paraganglioma and neuroblastoma.



68Ga-PSMA PET-CT
Prostate specific membrane antigen (PSMA) is a specific PET tracer used in prostate cancer with following indications.

  • For detection and staging of disease
  • For evaluation of response, differentiate between responder & non responder
  • Effectiveness of treatment
  • Detection of early recurrence
  • RT planning
  • PET guided biopsy

18F-DOPA PET-CT

18F-fluoro-3,4-dihydroxyphenylalnine (18F-DOPA) is a PET tracer that measures the uptake of dopamine precursors for assessment of presynaptic dopaminergic integrity. It is the standard PET used in Parkinson’s disease (PD). In oncology, it is the tracer of choice in suspected medullary thyroid carcinoma (MTC) and high grade gliomas recurrence.

18F-FES PET-CT

18F-Fluoroestradiol (FES) PET is useful in estrogen receptor (ER) positive breast cancer. It is recently FDA approved for recurrent or metastatic breast cancer patients as an adjunct to biopsy. Establishing ER positive status in each metastatic breast cancer sites will help in selecting the appropriate and effective treatment.click here

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